Myelodysplasi in English with contextual examples - MyMemory

Targeting chronic lymphocytic leukemia cells using anti-ROR1

Alkylation of a base may change the normal base pairing. For example, the alkylating agent EMS converts guanine to 7-ethylguanine which pairs with thymine. The mispairing will lead to mutation. Learn alkylating agents chemotherapy with free interactive flashcards. Choose from 500 different sets of alkylating agents chemotherapy flashcards on Quizlet. Cyclosporamide is a classical example of the role of the host metabolism in the activation of an alkylating agent and is one or the most widely used agents of this class. It was hoped that the cancer cells might posses enzymes capable of accomplishing the cleavage, thus resulting in the selective production of an activated nitrogen mustard in the malignant cells.

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2016-07-02 Antimetabolites interfere with DNA and RNA synthesis by acting as false metabolites, which are incorporated into the DNA strand or block essential enzymes, so that DNA synthesis is prevented.13 Most agents are cell cycle phase specific for S phase. These agents are most effective when used against rapidly cycling cell populations and are consequently more effective against 2020-03-05 Translations in context of "alkylating agent" in English-German from Reverso Context: The process of claim 9 wherein the secondary stage olefinic alkylating agent is comprised of propylene. There are five traditional categories of alkylating agents: Nitrogen mustards (eg, bendamustine, Alkylating agents can be used to treat a variety of cancers. Cyclophosphamide, which is also the most commonly used alkylating agent, can be used to treat lymphomas, breast, lung, ovarian and endometrium cancers.

Examples of alkylating agents include busulfan, cisplatin, carboplatin, chlorambucil, cyclophosphamide, ifosfamide, dacarbazine (DTIC), mechlorethamine  27 Nov 2019 Examples of basic alkyl group structures. Alkylating agents are chemicals that when they encounter the bases that make up DNA-guanine,  Alkylating agent definition: any cytotoxic drug containing alkyl groups, such as chlorambucil , that acts by Examples of 'alkylating agent' in a sentence.

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Se hela listan på chemocare.com 2021-03-15 · Severe suppression of the hematopoietic system can be caused by alkylating agents (e.g., cyclophosphamide, busulfan), antifolates (e.g. methotrexate), pyrimidine antagonists; (e.g. 5-FU, cytarabine), purine antagonists (e.g., 6-MP), taxanes (e.g., paclitaxel), anthracyclines (e.g., doxorubicin, daunorubicin) Alkylating agents, includ-ing carmustine (bischloroethyl nitrosourea, or BCNU), lomus-tine (chloroethylnitrosourea), and temozolomide, readily cross the blood-brain barrier and have shown the most activity against malignant glioma. However, despite the ability of these agents to achieve therapeutic concentrations in the brain, malignant gliomas 2017-03-27 · Alkylating agents usually induce mispairing between bases.

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canadian pharmacy viagra[/URL – said conservative agents, depletion, iritis; generic levitra vardenafil 20mg[/URL – examples subsequently, scrotum, justifying vardenafil 20mg globally articulations lecithin alkylating intimate multiforme:  Examples of obstructive lung diseases are asthma COPD Systemic chemotherapypreferred initial treatment alkylating agents for patients who  from a medicines dispensing system will respond well to alkylating agents. Financial Sector Donde consigo viagra en monterrey Examples of such  Krall, Uthoff, and Harley (1975) analyzed data from a study on multiple myeloma in which researchers treated 65 patients with alkylating agents. The model can  responses to iodoacetamide, a nonspecific cysteine-alkylating compound 38 .

Translations in context of "alkylating agent" in English-French from Reverso Context: The alpha-methylbenzylalcohol acts as an alkylating agent. Alkylating antineoplastic agent An alkylating antineoplastic agent is an alkylating agent agents, limpet attachment, and monoalkylating agents; 4 Examples  Alkylating Agents · Mustard gas derivatives: Mechlorethamine, Cyclophosphamide, Chlorambucil, Melphalan, and Ifosfamide.
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Common alkylating agents are Methylhydrazine, Temozolomide, Dacarbazine, Busulfan, Thio-TEPA, Carmustine, lomustine Dimethyl sulfate, Ethyl ethane sulfate. Agents include: Busulfan; Cyclophosphamide; Melphalan; Nursing Points General. Alkylating agents work to destroy DNA and block replication of cells in any phase of the cell cycle → even cells that are not rapidly diving in G0→ this makes it a good option for slower-growing cancers; Two sub-types exist 2017-10-30 · Alkylating agents 1.

These drugs are cell-cycle non-specific.
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Base Excision Repair - an overview ScienceDirect Topics

The risk of leukemia after getting alkylating agents is highest about 5 to 10 years after treatment.